San Francisco, CA to Manchester flights from $349

Travelers frequently search for route combinations, such as San Francisco and Las Vegas, Paris, Barcelona, Denver, Washington, D.C., Mexico City, Chicago, Guadalajara, London, Atlanta, Rome, Austin, Lisbon, Madrid, New York, Dublin, Amsterdam, New Orleans, Berlin, Athens.

Travelers frequently search for route combinations, such as Manchester and New York, Los Angeles, Tel Aviv, Denver, Dallas, Boston, Orlando, London, Washington, D.C., Detroit, Istanbul, Dublin, Madrid, Barcelona, Amman, Raleigh, Athens, Minneapolis, Copenhagen, Chicago.

The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, Oakland International, San Jose International, Stockton Metropolitan, Monterey Regional, Charles M. Schulz–Sonoma County, Merced Regional, Buchanan Field.

The main airport in Manchester is Manchester. It is also served by London Stansted, Luton, Manchester, Birmingham, Liverpool John Lennon, Bristol, Leeds Bradford, Newcastle, East Midlands, Isle of Man.

A number of bus and train companies depart from San Francisco, including Greyhound.

Yes, it's possible to combine different modes of transport between San Francisco and Manchester thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between San Francisco and Manchester can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between San Francisco and Manchester with easyJet, United Airlines, British Airways, Alaska Airlines, Aer Lingus.

If you don’t have specific dates for your trip between San Francisco and Manchester, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.