San Francisco to Santa Ana flights from $146

Flights starting at $146. Choose between United Airlines, Alaska Airlines, or Frontier Airlines to find the best price.

Why travel with Kiwi.com?
Best price

100+ million searches a day to find you the best available price.

Unique content

Explore unique options you won’t find anywhere else.

Travel hacks

Discover flight options and prices the airlines don’t want you to see.

Travelers usually depart from San Francisco International, San Francisco, CA Bus Stop, San Francisco, CA Train Station, San Francisco, CA - Salesforce Plaza, or San Francisco, CA - Fisherman’s Wharf when they travel from San Francisco to Santa Ana. Book your trip to arrive at John Wayne, or Santa Ana, CA Train Station. The distance between San Francisco and Santa Ana is 599 km. The most popular airlines for this route are United Airlines, Alaska Airlines, Frontier Airlines, Spirit Airlines, and Delta Air Lines. San Francisco and Santa Ana have 145 direct flights per week.

Weekly direct flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Direct flights1211111212810
Fly direct with

Alaska Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

United Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Check-in for a flight from San Francisco to Santa Ana

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
United AirlinesUALUAYesNo
Alaska AirlinesASAASYesOpens 24 days before flight
Closes 1 hours before flight
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight

Santa Ana travel tips

1) Enjoy an evening in an Art Deco theatre

The Yost Theater was built in 1913 as a place for entertainment and silent movies. Today, the elegant building is still a thriving arts venue, hosting concerts, club nights and pop-up restaurants.

2) Oranges used to be grapes

Until the 1880s, Orange County was a big wine production area with over 50 vineyards. When a disease destroyed all the grapes, the damaged vineyards were replaced with new orange trees that gave the area its name.

3) Dine in an old mine

Enjoy panoramic views and incredible food from this disused silver mine at the top of a hill. Serving globally inspired dishes, this rustic restaurant transports you back to the mining era while you have dinner or a champagne brunch.

Learn more about COVID-19 restrictions in United States in our dedicated Stories article.

Frequently asked questions

How long does it take to travel from San Francisco to Santa Ana?
A one-way nonstop (direct) flight between San Francisco and Santa Ana takes around 1.6 hours.
What is the flight distance between San Francisco and Santa Ana?
The flight distance between San Francisco and Santa Ana is 599 km.
What airlines offer nonstop (direct) flights between San Francisco and Santa Ana?
Several carriers operate flights between San Francisco and Santa Ana. Airlines offering nonstop (direct) flights include Alaska Airlines, United Airlines.
What are the most popular routes to and from San Francisco?
Travelers frequently search for route combinations, such as San Francisco and Las Vegas, Paris, Barcelona, Denver, Washington, D.C., Mexico City, Chicago, Guadalajara, London, Atlanta, Rome, Austin, Lisbon, Madrid, New York, Dublin, Amsterdam, New Orleans, Berlin, Athens.
What are the most popular routes to and from Santa Ana?
Travelers frequently search for route combinations, such as Santa Ana and Denver, Las Vegas, Austin, Phoenix, Detroit, Sacramento, Charlotte, Dallas, New York, Washington, D.C., San Jose, Chicago, Oakland, Portland, Atlanta, Seattle, Minneapolis, Houston, San Antonio, Salt Lake City.
What airports are near San Francisco?
The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, Oakland International, San Jose International, Monterey Regional, Stockton Metropolitan, Charles M. Schulz–Sonoma County, Merced Regional, Buchanan Field.
What airports are near Santa Ana?
The main airport in Santa Ana is John Wayne. It is also served by San Diego International, Ontario International, John Wayne, Tijuana International, Hollywood Burbank, Palm Springs International, Santa Barbara Municipal, Imperial County, Long Beach, Meadows Field.
What buses and trains depart from San Francisco?
A number of bus and train companies depart from San Francisco, including Greyhound.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between San Francisco and Santa Ana?
Yes, it's possible to combine different modes of transport between San Francisco and Santa Ana thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between San Francisco and Santa Ana can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.
What is Virtual Interlining and how do I use it?
Which airlines fly between San Francisco and Santa Ana?
When's the best time to travel between San Francisco and Santa Ana?
What flights operate between San Francisco and Santa Ana?
How many airports are there near San Francisco?
How many airports are there near Santa Ana?
Is it possible to reach San Francisco by bus or train?
What time do nonstop (direct) flights between San Francisco and Santa Ana depart?
What time do nonstop (direct) flights between San Francisco and Santa Ana arrive?
What time do flights between San Francisco and Santa Ana depart?
What time do flights between San Francisco and Santa Ana arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

Explore alternative trips

Flights from San Francisco

Flights to Santa Ana

Popular routes

Find the best connection from San Francisco to Santa Ana

Search, compare, and book flights, trains, or buses to get there.

Search flights, trains & buses