Cheap flights from San Luis Obispo to Panama City from $301

Travelers frequently search for route combinations, such as San Luis Obispo and Seattle, Puerto Vallarta, Portland, Denver, Spokane, Columbus, Palm Springs, Detroit, Omaha, Sylhet, Tijuana, Cúcuta, Tirana, Honolulu, Saint Thomas, Santa Cruz de la Sierra, Puerto Escondido, Oaxaca, Norfolk, Indianapolis, Madrid.

Travelers frequently search for route combinations, such as Panama and Houston, Los Angeles, New York, Miami, Atlanta, Dallas, Bocas Town, Bocas del Toro, Washington, D.C., San José, Detroit, San Juan, Orlando, Medellín, David, Chiriquí, San Francisco, Salt Lake City, Las Vegas, Chicago, Guatemala City, Bogotá.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, San Luis Obispo County Regional, Santa Maria Public, Meadows Field.

The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.

Currently, you can fly between San Luis Obispo and Panama with Copa Airlines, Hawaiian Airlines, Alaska Airlines, United Airlines, Avianca.

If you don’t have specific dates for your trip between San Luis Obispo and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Luis Obispo and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, San Luis Obispo County Regional, Santa Maria Public, Meadows Field

There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama.