Cheap flights from Houston to Panama City from $395

Travelers frequently search for route combinations, such as Houston and Mexico City, Calgary, Guadalajara, New York, Los Angeles, Toronto, Chicago, Orlando, Las Vegas, Denver, Atlanta, Bogotá, Medellín, Vancouver, Miami, Tokyo, Dallas, Washington, D.C., Lima, Montreal.

Travelers frequently search for route combinations, such as Panama and Miami, New York, Los Angeles, Boston, Detroit, Bocas Town, Bocas del Toro, Washington, D.C., Chicago, Denver, Atlanta, Las Vegas, Minneapolis, San Francisco, Medellín, Austin, Fort Lauderdale, Raleigh, Salt Lake City, Cincinnati, Bogotá.

Houston is mainly served by George Bush Intercontinental. But there are other airports nearby, including William P. Hobby.

The main airport in Houston is George Bush Intercontinental. It is also served by Austin–Bergstrom International, Lake Charles Regional, Victoria Regional, Easterwood.

Currently, you can fly between Houston and Panama with Avianca, Copa Airlines, Frontier Airlines, Wingo airlines, VivaAerobus.

If you don’t have specific dates for your trip between Houston and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Houston and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Houston. The main one is George Bush Intercontinental and other nearby airports include Austin–Bergstrom International, Lake Charles Regional, Victoria Regional, Easterwood

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Houston, such as morning, afternoon, evening, or night, or select the exact hours for departure.