Cheap flights from Chicago to Santiago de Chile from £225

Travelers frequently search for route combinations, such as Chicago and London, Mexico City, Guadalajara, Orlando, Atlanta, Dallas, Phoenix, Miami, New York, Las Vegas, Cancún, Denver, León, Fort Lauderdale, Los Angeles, Tampa, Morelia, San Francisco, Houston, Philadelphia.

Travelers frequently search for route combinations, such as Santiago de Chile and London, Buenos Aires, Puerto Natales, Lima, Calama, Punta Arenas, São Paulo, Mendoza, Manchester, Easter Island, Bogotá, Rio de Janeiro, Bariloche, Miami, Glasgow, Edinburgh, Medellín, Cusco, Puerto Montt, Montevideo.

Chicago is mainly served by O Hare International. But there are other airports nearby, including Chicago Midway International, Chicago Rockford International.

The main airport in Chicago is O Hare International. It is also served by Gerald R. Ford International, General Mitchell International, South Bend International, Dane County Regional, Fort Wayne International, General Wayne A. Downing Peoria International, Quad City International, University of Illinois Willard, Muskegon County, Central Illinois Regional.

The main airport in Santiago de Chile is Comodoro Arturo Merino Benítez International. It is also served by Comodoro Arturo Merino Benítez International.

Currently, you can fly between Chicago and Santiago de Chile with Spirit Airlines, LATAM Airlines, Copa Airlines, Avianca, Frontier Airlines.

If you don’t have specific dates for your trip between Chicago and Santiago de Chile, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Chicago and Santiago de Chile, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Chicago. The main one is O Hare International and other nearby airports include Gerald R. Ford International, General Mitchell International, South Bend International, Dane County Regional, Fort Wayne International, General Wayne A. Downing Peoria International, Quad City International, University of Illinois Willard, Muskegon County, Central Illinois Regional