Cheap flights from Chicago to Santiago de los Caballeros from £143

Travelers frequently search for route combinations, such as Chicago and London, Mexico City, Guadalajara, Orlando, Atlanta, Dallas, Phoenix, Miami, New York, Las Vegas, Cancún, Denver, León, Fort Lauderdale, Los Angeles, Tampa, Morelia, San Francisco, Houston, Philadelphia.

Travelers frequently search for route combinations, such as Santiago de los Caballeros and London, New York, Medellín, Fort Lauderdale, Atlanta, San Juan, Cali, Miami, Boston, Norfolk, Nashville, Minneapolis, Guatemala City, Orlando, Salt Lake City, Philadelphia, Oaxaca, Dallas, Cleveland, Tampa.

Chicago is mainly served by O Hare International. But there are other airports nearby, including Chicago Midway International, Chicago Rockford International.

The main airport in Chicago is O Hare International. It is also served by Gerald R. Ford International, General Mitchell International, South Bend International, Dane County Regional, Quad City International, Fort Wayne International, General Wayne A. Downing Peoria International, Central Illinois Regional, Muskegon County, University of Illinois Willard.

The main airport in Santiago de los Caballeros is Cibao International. It is also served by Las Américas International, Cap-Haïtien International, Cibao International, La Romana International, La Isabela International, Gregorio Luperón International, Samaná El Catey International.

Currently, you can fly between Chicago and Santiago de los Caballeros with JetBlue Airways, Spirit Airlines, United Airlines, Frontier Airlines, Allegiant Air.

If you don’t have specific dates for your trip between Chicago and Santiago de los Caballeros, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Chicago and Santiago de los Caballeros, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Chicago. The main one is O Hare International and other nearby airports include Gerald R. Ford International, General Mitchell International, South Bend International, Dane County Regional, Quad City International, Fort Wayne International, General Wayne A. Downing Peoria International, Central Illinois Regional, Muskegon County, University of Illinois Willard