Cheap flights from Des Moines to Charlotte from £110

Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Istanbul, Austin, Santa Ana, Orlando, Guadalajara, Tampa, Houston, Sarasota, Shanghai, Winnipeg, Montreal, Kathmandu, Punta Gorda, Malé, Boston, Monrovia, Mexico City.

Travelers frequently search for route combinations, such as Charlotte and London, New York, Manchester, Orlando, Edinburgh, Belfast, Miami, Dallas, Chicago, Philadelphia, Houston, Boston, Fort Lauderdale, Bogotá, Los Angeles, Guadalajara, San José, Mexico City, Washington, D.C., Denver.

The main airport in Des Moines is Des Moines International. It is also served by Eppley Airfield, Des Moines International, The Eastern Iowa, Mason City Municipal, Fort Dodge Regional, Waterloo Regional, Kirksville Regional, Southeast Iowa Regional, Sioux Gateway.

The main airport in Charlotte is Charlotte Douglas International. It is also served by Raleigh–Durham International, Charlotte Douglas International, Asheville Regional, Myrtle Beach International, Greenville–Spartanburg International, Columbia Metropolitan, Piedmont Triad International, Tri-Cities Regional, Roanoke–Blacksburg Regional, Concord Regional.

Currently, you can fly between Des Moines and Charlotte with United Airlines, Allegiant Air, Frontier Airlines, Spirit Airlines, JetBlue Airways.

If you don’t have specific dates for your trip between Des Moines and Charlotte, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Des Moines and Charlotte, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Eppley Airfield, Des Moines International, The Eastern Iowa, Mason City Municipal, Fort Dodge Regional, Waterloo Regional, Kirksville Regional, Southeast Iowa Regional, Sioux Gateway

There are a number of airports in and around Charlotte. The main one is Charlotte Douglas International and other nearby airports include Raleigh–Durham International, Charlotte Douglas International, Asheville Regional, Myrtle Beach International, Greenville–Spartanburg International, Columbia Metropolitan, Piedmont Triad International, Tri-Cities Regional, Roanoke–Blacksburg Regional, Concord Regional.