Cheap flights from Des Moines to Brussels from £252

Cheap flights from Des Moines to Brussels from £252

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2 stops
Fri, Feb 27
Des Moines DSMBrussels BRU
£252
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2 stops
Wed, Feb 25
Des Moines DSMBrussels BRU
£392
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2 stops
Wed, Feb 25
Des Moines DSMBrussels BRU
£402
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2 stops
Wed, Feb 25
Des Moines DSMBrussels BRU
£405
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1 stop
Wed, Feb 25
Des Moines DSMBrussels BRU
£406
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1 stop
Wed, Feb 25
Des Moines DSMBrussels BRU
£406
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1 stop
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£551
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1 stop
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£552
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2 stops
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£552
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2 stops
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£553
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1 stop
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£562
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2 stops
Wed, Feb 25 – Mon, Mar 2
Des Moines DSMBrussels BRU
£563
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How much do flights to Brussels cost?

Cheapest one-way trip

£252

Cheapest round-trip

£551

Average round-trip

£715

Includes rare itinerary

Travel hack

Most popular airline

Ryanair

Getting from Brussels airport to the city center

Fastest option: Airport Express train. Best value: STIB bus lines and regional trains.

Brussels is served by Brussels Airport (BRU), located 12 km northeast of the city center. A variety of airport transfers to city center destinations are available, including direct trains, buses, taxis, ride-hailing services, and private transfers. The Airport Express train offers the quickest connection to Brussels-Central, Brussels-Midi, and Brussels-Nord stations. Budget travelers can opt for STIB bus lines or regional trains. Journey times and costs vary depending on your final destination and traffic conditions.

Transport Option

Typical time

Typical cost

Frequency

Best for

17-21 min

€12-€14 (standard single fare)

every 10–15 min (traffic dependent)

fastest to city center

30-45 min

€3-€4 (STIB single ticket)

every 20–30 min (traffic dependent)

budget travelers

25-40 min

€3-€4 (STIB single ticket)

every 20–30 min (traffic dependent)

north Brussels destinations

20-45 min

€45-€55 (metered; varies by traffic)

on-demand 24/7 (traffic dependent)

door-to-door convenience

20-45 min

€30-€50 (varies with demand)

on-demand 24/7 (traffic dependent)

app-based booking

20-40 min

€60-€90 (pre-booked fixed rate)

pre-booked (traffic dependent)

groups or business travel

20-45 min

€35-€80 (per day; varies by provider)

on-demand (traffic dependent)

flexibility and onward travel

Notes:

  • Prices in EUR; table created in 2025 and subject to change.
  • The Airport Express train departs from the airport's underground station (Level -1).
  • STIB tickets can be purchased at the airport or via the STIB-MIVB app.
  • Taxi fares are metered; ride-hailing prices vary with demand. Road traffic can significantly affect journey times.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to Brussels

Depart from
Des Moines International
Arrive to
Brussels
Average flights per week
337
Flight distance
Worth visiting
Andaz Amsterdam Prinsengracht - Anne Frank Huis - IJsselmonde - La Grand-Place, Brussels - Rijksmuseum - Van Gogh Museum - Voorne-Putten - Windmill Complex at Kinderdijk

Check-in for a flight from Des Moines to Brussels

NameCarrier codeIATA CodePassport needed during booking
RyanairRYRFRNo
Aer LingusEINEINo
Allegiant AirAAYG4No
Air FranceAFRAFNo
LufthansaDLHLHNo

Online check-in is not available for these airlines.

Weather in Brussels

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January5°C1°C
February7°C1°C
March10°C3°C
April14°C5°C
May17°C8°C
June21°C12°C
July23°C14°C
August23°C14°C
September20°C11°C
October15°C8°C
November10°C5°C
December6°C2°C
Hottest Month
23°C
August
Coldest month
1°C
January
Sunny days
265
days per year
Snow days
5
days per year

14 day forecast

Sunday
15 Feb
86%
4°C0°C
22 Feb
87%
1°C1°C
Monday
16 Feb
89%
7°C2°C
23 Feb
88%
4°C1°C
Tuesday
17 Feb
87%
7°C4°C
24 Feb
86%
7°C3°C
Wednesday
18 Feb
80%
5°C0°C
25 Feb
9°C2°C
Thursday
19 Feb
75%
0°C-1°C
26 Feb
85%
10°C8°C
Friday
20 Feb
75%
0°C-2°C
27 Feb
89%
9°C6°C
Saturday
21 Feb
83%
1°C0°C
28 Feb
62%
3°C-1°C
Book your trip to arrive at Brussels, Brussels South Charleroi, or Antwerp International. The most popular airlines for this route are Ryanair, Aer Lingus, Allegiant Air, Air France, and Lufthansa. Des Moines and Brussels have 337 direct flights per week. When you arrive at Brussels, consider visiting Andaz Amsterdam Prinsengracht, Anne Frank Huis, IJsselmonde, La Grand-Place, Brussels, Rijksmuseum, Van Gogh Museum, Voorne-Putten, and Windmill Complex at Kinderdijk.

Frequently asked questions

What are the most popular routes to and from Des Moines?
Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Istanbul, Austin, Santa Ana, Orlando, Guadalajara, Tampa, Houston, Sarasota, Shanghai, Winnipeg, Montreal, Kathmandu, Punta Gorda, Malé, Boston, Monrovia, Mexico City.
What are the most popular routes to and from Brussels?
Travelers frequently search for route combinations, such as Brussels and London, Manchester, Edinburgh, Bucharest, Tirana, Budapest, Warsaw, Sofia, Chișinău, Tel Aviv, Barcelona, Athens, Prague, Lisbon, Birmingham, Cluj-Napoca, Istanbul, Madrid, Vienna, Vilnius.
What airports are near Des Moines?
The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Kirksville Regional, Sioux Gateway, Fort Dodge Regional, Mason City Municipal, Waterloo Regional.
What airports are near Brussels?
The main airport in Brussels is Brussels. It is also served by Charles de Gaulle Airport, Amsterdam Airport Schiphol, Beauvais–Tillé, Düsseldorf International Airport, Cologne Bonn Airport, Frankfurt–Hahn, Eindhoven, Luxembourg, Weeze, Dortmund.
Which airlines fly between Des Moines and Brussels?
Currently, you can fly between Des Moines and Brussels with Ryanair, Aer Lingus, Allegiant Air, Air France, Lufthansa.
When’s the best time to travel between Des Moines and Brussels?
If you don’t have specific dates for your trip between Des Moines and Brussels, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between Des Moines and Brussels?
Traveling between Des Moines and Brussels, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.
How many airports are there near Des Moines?
There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Southeast Iowa Regional, Kirksville Regional, Sioux Gateway, Fort Dodge Regional, Mason City Municipal, Waterloo Regional
How many airports are there near Brussels?
There are a number of airports in and around Brussels. The main one is Brussels and other nearby airports include Charles de Gaulle Airport, Amsterdam Airport Schiphol, Beauvais–Tillé, Düsseldorf International Airport, Cologne Bonn Airport, Frankfurt–Hahn, Eindhoven, Luxembourg, Weeze, Dortmund.
What time do nonstop (direct) flights between Des Moines and Brussels depart?
What time do nonstop (direct) flights between Des Moines and Brussels arrive?
What time do flights between Des Moines and Brussels depart?
What time do flights between Des Moines and Brussels arrive?

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