Cheap flights from Des Moines to Lyon from £280

Cheap flights from Des Moines to Lyon from £280

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2 stops
Mon, Jul 27
Des Moines DSMLyon LYS
£280
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2 stops
Mon, Jul 27
Des Moines DSMLyon LYS
£311
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2 stops
Mon, Jul 27
Des Moines DSMLyon LYS
£350
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2 stops
Thu, Jul 30
Des Moines DSMLyon LYS
£355
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2 stops
Mon, Jul 27
Des Moines DSMLyon LYS
£368
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2 stops
Mon, Jul 27
Des Moines DSMLyon LYS
£392
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2 stops
Thu, Jul 30 – Thu, Aug 6
Des Moines DSMLyon LYS
£872
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3 stops
Thu, Jul 30 – Thu, Aug 6
Des Moines DSMLyon LYS
£886
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3 stops
Thu, Jul 30 – Thu, Aug 6
Des Moines DSMLyon LYS
£905
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3 stops
Thu, Jul 30 – Thu, Aug 6
Des Moines DSMLyon LYS
£934
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2 stops
Thu, Jul 30 – Thu, Aug 6
Des Moines DSMLyon LYS
£972
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2 stops
Mon, Jul 27 – Fri, Jul 31
Des Moines DSMLyon LYS
£1,255
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How much do flights to Lyon cost?

Cheapest one-way trip

£280

Cheapest round-trip

£872

Average round-trip

£1,021

Includes rare itinerary

Travel hack

Most popular airline

Allegiant Air

Getting from Lyon airport to the city center

Fastest option: Rhônexpress tram. Best value: TCL bus lines.

Lyon is served by Lyon-Saint Exupéry Airport (LYS), located 25 km east of the city center. A variety of airport transfers to city center destinations are available, including the dedicated Rhônexpress tram, public buses, taxis, ride-hailing services, and private transfers. Journey times and costs vary depending on the transport option, time of day, and traffic conditions.

Transport Option

Typical time

Typical cost

Frequency

Best for

29-32 min

€16 – €17; online vs on-the-spot fares

every 15 min (traffic dependent)

fastest to city center

20-30 min

€2 – €3; standard TCL ticket; connect to tram T3

every 20–30 min (traffic dependent)

budget travelers

25-50 min

€55 – €80; metered; varies by traffic and destination

on-demand 24/7 (traffic dependent)

door-to-door with luggage

25-50 min

€40 – €70; surge pricing may apply

on-demand 24/7 (traffic dependent)

app-based convenience

25-45 min

€70 – €120; pre-booked; fixed price

pre-booked (traffic dependent)

groups or business travelers

25-50 min

€30 – €80; per day; varies by provider

on-demand (traffic dependent)

exploring the region

Notes:

  • Prices in EUR; table created in 2025 and subject to change.
  • Rhônexpress tickets can be purchased online at a discount or at the airport.
  • TCL bus 47 connects to tram T3 at Meyzieu ZI for onward travel to central Lyon.
  • Taxi fares are metered; ride-hailing prices vary with demand. Road traffic can significantly affect journey times.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to Lyon

Depart from
Des Moines International
Arrive to
Lyon–Saint-Exupéry
Average flights per week
280
Flight distance
Worth visiting
Aiguille Du Midi, France - Lake Geneva - Mont Blanc

Check-in for a flight from Des Moines to Lyon

NameCarrier codeIATA CodePassport needed during booking
Allegiant AirAAYG4No
easyJetEZYU2Yes
Aer LingusEINEINo
Air FranceAFRAFNo
JetBlue AirwaysJBUB6No

Online check-in is not available for these airlines.

Weather in Lyon

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January6°C0°C
February8°C1°C
March12°C3°C
April16°C6°C
May19°C9°C
June25°C13°C
July27°C15°C
August27°C16°C
September23°C12°C
October17°C9°C
November11°C4°C
December7°C1°C
Hottest Month
27°C
August
Coldest month
0°C
January
Sunny days
270
days per year
Snow days
7
days per year

14 day forecast

Saturday
11 Jul
57%
34°C19°C
18 Jul
30°C17°C
Sunday
12 Jul
34°C18°C
19 Jul
28°C18°C
Monday
13 Jul
37°C20°C
20 Jul
25°C16°C
Tuesday
14 Jul
17%
40°C21°C
21 Jul
11%
25°C15°C
Wednesday
15 Jul
57%
35°C21°C
22 Jul
36%
30°C18°C
Thursday
16 Jul
65%
37°C20°C
23 Jul
31°C18°C
Friday
17 Jul
64%
32°C18°C
24 Jul
35°C18°C
The most popular airlines for this route are Allegiant Air, easyJet, Aer Lingus, Air France, and JetBlue Airways. Des Moines and Lyon have 280 direct flights per week. When you arrive at Lyon, consider visiting Aiguille Du Midi, France, Lake Geneva, and Mont Blanc.

Frequently asked questions

What are the most popular routes to and from Des Moines?
Travelers frequently search for route combinations, such as Des Moines and Las Vegas, Nashville, Phoenix, Istanbul, Austin, Santa Ana, Orlando, Guadalajara, Tampa, Houston, Sarasota, Shanghai, Winnipeg, Montreal, Kathmandu, Punta Gorda, Malé, Boston, Monrovia, Mexico City.
What are the most popular routes to and from Lyon?
Travelers frequently search for route combinations, such as Lyon and London, Manchester, Glasgow, Edinburgh, Birmingham, Bristol, Kraków, Barcelona, Madrid, Tel Aviv, Bucharest, Tirana, Athens, Prague, Istanbul, Sofia, Rome, Oslo, Budapest, Berlin.
What airports are near Des Moines?
The main airport in Des Moines is Des Moines International. It is also served by Des Moines International, Eppley Airfield, The Eastern Iowa, Kirksville Regional, Southeast Iowa Regional, Mason City Municipal, Fort Dodge Regional, Waterloo Regional, Sioux Gateway.
What airports are near Lyon?
The main airport in Lyon is Lyon–Saint-Exupéry. It is also served by Geneva, Turin, Nîmes–Alès–Camargue–Cévennes, Dole–Jura, Bern, Clermont-Ferrand Auvergne, Alpes–Isère, Chambéry, Le Puy – Loudes, Saint-Étienne–Bouthéon.
Which airlines fly between Des Moines and Lyon?
Currently, you can fly between Des Moines and Lyon with Allegiant Air, easyJet, Aer Lingus, Air France, JetBlue Airways.
When’s the best time to travel between Des Moines and Lyon?
If you don’t have specific dates for your trip between Des Moines and Lyon, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between Des Moines and Lyon?
Traveling between Des Moines and Lyon, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.
How many airports are there near Des Moines?
There are a number of airports in and around Des Moines. The main one is Des Moines International and other nearby airports include Des Moines International, Eppley Airfield, The Eastern Iowa, Kirksville Regional, Southeast Iowa Regional, Mason City Municipal, Fort Dodge Regional, Waterloo Regional, Sioux Gateway
How many airports are there near Lyon?
There are a number of airports in and around Lyon. The main one is Lyon–Saint-Exupéry and other nearby airports include Geneva, Turin, Nîmes–Alès–Camargue–Cévennes, Dole–Jura, Bern, Clermont-Ferrand Auvergne, Alpes–Isère, Chambéry, Le Puy – Loudes, Saint-Étienne–Bouthéon.
What time do nonstop (direct) flights between Des Moines and Lyon depart?
What time do nonstop (direct) flights between Des Moines and Lyon arrive?
What time do flights between Des Moines and Lyon depart?
What time do flights between Des Moines and Lyon arrive?

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