Cheap flights from Madrid to Mytilene from £120

Travelers frequently search for route combinations, such as Madrid and London, Manchester, Edinburgh, Lisbon, Paris, Amsterdam, Barcelona, Rome, Glasgow, Bristol, Tenerife, Belfast, Birmingham, Mexico City, Tel Aviv, Milan, Newcastle upon Tyne, Warsaw, Budapest, Berlin.

Travelers frequently search for route combinations, such as Mytilene and London, Birmingham, Athens, Tel Aviv, Amsterdam, Bucharest, Thessaloniki, Tirana, Heraklion, Stockholm, Larnaca, Vienna, Geneva, Dublin, Oslo, Berlin, Santorini, Rhodes, Lisbon, Cluj-Napoca.

The main airport in Madrid is Adolfo Suárez Madrid–Barajas. It is also served by Valladolid, Salamanca.

The main airport in Mytilene is Mytilene International. It is also served by Mytilene International, Balıkesir Koca Seyit, Chios Island National, Çanakkale.

Currently, you can fly between Madrid and Mytilene with Aegean, Ryanair, SKY express, Iberia Airlines, Wizz Air Malta.

If you don’t have specific dates for your trip between Madrid and Mytilene, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Madrid and Mytilene, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Madrid. The main one is Adolfo Suárez Madrid–Barajas and other nearby airports include Valladolid, Salamanca

There are a number of airports in and around Mytilene. The main one is Mytilene International and other nearby airports include Mytilene International, Balıkesir Koca Seyit, Chios Island National, Çanakkale.