Cheap flights from Matamoros to Santa Ana from £218

Travelers frequently search for route combinations, such as Matamoros and Mexico City, Monterrey, Tapachula, Mexicali, León, Hermosillo, Puerto Vallarta, Lagos, Bogotá, Atlanta, Cancún, Boston, Aguascalientes, Buenos Aires, Lviv, Oaxaca, Key West, San Antonio, Istanbul, Madrid.

Travelers frequently search for route combinations, such as Santa Ana and Provo, Calgary, Las Vegas, San Francisco, Vancouver, London, Seattle, Phoenix, Oakland, Denver, Edmonton, Eugene, Boise, Colorado Springs, Hong Kong, Des Moines, Medford, Kelowna, Idaho Falls, Dallas.

The main airport in Matamoros is Matamoros International. It is also served by General Lucio Blanco International, McAllen Miller International, Matamoros International, Brownsville/South Padre Island International, Corpus Christi International, Valley International.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Hollywood Burbank, Palm Springs International, Santa Barbara Municipal, Long Beach, McClellan–Palomar, Imperial County.

Currently, you can fly between Matamoros and Santa Ana with AeroMexico, Volaris, VivaAerobus, BREEZE, Frontier Airlines.

If you don’t have specific dates for your trip between Matamoros and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Matamoros and Santa Ana, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Matamoros. The main one is Matamoros International and other nearby airports include General Lucio Blanco International, McAllen Miller International, Matamoros International, Brownsville/South Padre Island International, Corpus Christi International, Valley International

There are a number of airports in and around Santa Ana. The main one is John Wayne and other nearby airports include Tijuana International, San Diego International, Ontario International, John Wayne, Hollywood Burbank, Palm Springs International, Santa Barbara Municipal, Long Beach, McClellan–Palomar, Imperial County.