Cheap flights from Panama City to Santa Ana from £255

Travelers frequently search for route combinations, such as Panama City and Providence, Austin, Cancún, St. Louis, Los Angeles, Nashville, Destin, Almaty, Albuquerque, Amritsar, Oklahoma City, Odessa, New Orleans, Hamburg, Fort Myers, Myrtle Beach, Tulsa, Guayaquil, Cape Town, Puerto Vallarta.

Travelers frequently search for route combinations, such as Santa Ana and Las Vegas, Phoenix, Denver, Provo, London, Seattle, Oakland, Portland, Minneapolis, Dallas, Austin, Vancouver, Boise, New York, Calgary, Sacramento, San Francisco, Reno, Cleveland, Salt Lake City.

Panama City is mainly served by Northwest Florida Beaches International. But there are other airports nearby, including Panama City-Bay Co International Airport.

The main airport in Panama City is Northwest Florida Beaches International. It is also served by Destin–Fort Walton Beach, Pensacola International, Tallahassee International, Montgomery Regional, Dothan Regional, Southwest Georgia Regional, Valdosta Regional.

The main airport in Santa Ana is John Wayne. It is also served by Los Angeles International, Tijuana International, San Diego International, John Wayne, Ontario International, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Hawthorne Municipal.

Currently, you can fly between Panama City and Santa Ana with United Airlines.

If you don’t have specific dates for your trip between Panama City and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Panama City and Santa Ana, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Panama City. The main one is Northwest Florida Beaches International and other nearby airports include Destin–Fort Walton Beach, Pensacola International, Tallahassee International, Montgomery Regional, Dothan Regional, Southwest Georgia Regional, Valdosta Regional