Cheap flights from Panama City to Key West from £324

Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Medellín, David, Chiriquí, Cartagena, Bogotá, San José, London, Managua, Cancún, Cali, Chitré, Caracas, Mexico City, Guatemala City, Puerto Vallarta, New York, Belize City, Lima, Barranquilla, Rio de Janeiro.

Travelers frequently search for route combinations, such as Key West and London, Tampa, Orlando, Tallahassee, Toronto, Fort Lauderdale, Pensacola, Chongqing, Nassau, Cancún, Providence, Grand Cayman, Saint Kitts, Odessa, Pasco, Cincinnati, Cairo, Bonaire, Tupelo, Bismarck.

Panama is mainly served by Tocumen International. But there are other airports nearby, including Albrook Marcos A. Gelabert International.

The main airport in Key West is Key West International. It is also served by Miami International, Key West International.

Currently, you can fly between Panama and Key West with Copa Airlines, BREEZE, Avianca, JetBlue Airways.

If you don’t have specific dates for your trip between Panama and Key West, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Panama and Key West, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Key West. The main one is Key West International and other nearby airports include Miami International, Key West International.

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Panama, such as morning, afternoon, evening, or night, or select the exact hours for departure.