Cheap flights from Rome, Italy to Santa Ana, CA

Travelers frequently search for route combinations, such as Rome and London, Manchester, Edinburgh, Dublin, Reykjavik, Toronto, Bristol, Birmingham, Montreal, Glasgow, Tallinn, Athens, Vienna, Vancouver, Amsterdam, Paris, Malta, Liverpool, Thessaloniki, Brussels.

Travelers frequently search for route combinations, such as Santa Ana and Austin, Toronto, Edmonton, London, Denver, Calgary, San Francisco, Portland, Seattle, Las Vegas, Reykjavik, Buffalo, Houston, Barcelona, Chennai, Charlotte, Birmingham, Fayetteville, Orlando, Dallas.

Rome is mainly served by Leonardo da Vinci–Fiumicino Airport. But there are other airports nearby, including Ciampino–G. B. Pastine International.

The main airport in Rome is Leonardo da Vinci–Fiumicino Airport. It is also served by Naples International, Florence, Marche Airport, San Francesco d Assisi, Abruzzo.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, Ontario International, John Wayne, Palm Springs International, Hollywood Burbank, Long Beach, Santa Barbara Municipal, Meadows Field, Hawthorne Municipal.

Yes, it's possible to combine different modes of transport between Rome and Santa Ana thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between Rome and Santa Ana can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.

Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.

Currently, you can fly between Rome and Santa Ana with Alaska Airlines, French Bee, Spirit Airlines, Vueling, Wizz Air Malta.

If you don’t have specific dates for your trip between Rome and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.