Cheap flights from Santa Cruz de la Sierra to Panama City from £280

Cheap flights from Santa Cruz de la Sierra to Panama City from £280

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1 stop
Wed, Mar 4
Santa Cruz de la Sierra VVIPanama PTY
£280
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1 stop
Thu, Mar 5
Santa Cruz de la Sierra VVIPanama PTY
£280
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1 stop
Wed, Mar 4
Santa Cruz de la Sierra VVIPanama PTY
£280
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1 stop
Thu, Mar 5
Santa Cruz de la Sierra VVIPanama PTY
£280
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2 stops
Thu, Mar 5
Santa Cruz de la Sierra VVIPanama PTY
£325
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1 stop
Thu, Mar 5
Santa Cruz de la Sierra VVIPanama BLB
£370
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1 stop
Wed, Mar 4 – Mon, Mar 9
Santa Cruz de la Sierra VVIPanama PTY
£542
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1 stop
Thu, Mar 5 – Tue, Mar 10
Santa Cruz de la Sierra VVIPanama PTY
£542
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1 stop
Wed, Mar 4 – Sun, Mar 8
Santa Cruz de la Sierra VVIPanama PTY
£542
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1 stop
Thu, Mar 5 – Sun, Mar 8
Santa Cruz de la Sierra VVIPanama PTY
£543
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1 stop
Thu, Mar 5 – Tue, Mar 10
Santa Cruz de la Sierra VVIPanama PTY
£564
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1 stop
Wed, Mar 4 – Sat, Mar 7
Santa Cruz de la Sierra VVIPanama PTY
£564
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How much do flights to Panama City cost?

Cheapest one-way trip

£280

Cheapest round-trip

£542

Average round-trip

£678

Includes rare itinerary

Travel hack

Most popular airline

Avianca

Getting from Panama City's airport to the city center

Fastest options: taxi or ride-hailing services. Best value: public bus or Metro connection.

Panama City is served by Tocumen International Airport (PTY), the main international gateway located 24 km northeast of the city center. The airport offers various airport transfers to city center destinations including taxis, ride-hailing services, public buses, and the Metro connection via Corredor Sur. Journey times typically range from 30 minutes to over an hour depending on traffic conditions, which can be significant during peak hours. A smaller domestic airport, Marcos A. Gelabert International Airport (PAC), also known as Albrook Airport, is located just 3 km from downtown within the city limits.

From Tocumen International Airport (PTY)

Transport Option

Typical Time

Typical Cost

Frequency

Best For

30-60 min

$30-$35 (fixed rate to city center)

on-demand 24/7 (traffic dependent)

convenience with luggage

30-60 min

$18-$30 (varies by demand and route)

on-demand 24/7 (traffic dependent)

budget-conscious travelers

60-90 min

$0.25-$1.25 (requires Metro card)

every 15-30 min (traffic dependent)

lowest cost option

45-75 min

$0.35 (requires feeder bus to station)

every 5-10 min (traffic dependent)

avoiding traffic

30-60 min

$40-$70 (pre-booked; price per vehicle)

pre-booked (traffic dependent)

groups or families

30-60 min

$35-$80 (per day; varies by vehicle)

on-demand (traffic dependent)

flexibility and exploration

From Marcos A. Gelabert International Airport (PAC)

Transport Option

Typical Time

Typical Cost

Frequency

Best For

10-20 min

$5-$10 (metered or negotiated)

on-demand (traffic dependent)

quick city access

15-30 min

$0.35 (short walk to station)

every 5-10 min

fast and affordable

Notes:

  • Prices in USD; table created in 2025 and subject to change.
  • Traffic in Panama City can be heavy, especially during rush hours (7-9 AM and 5-8 PM). Allow extra time.
  • The Metro requires a rechargeable Metro card, available at stations. Cash is not accepted on Metro or Metrobus.
  • Official airport taxis have fixed rates displayed at the taxi stand. Negotiate before boarding unofficial taxis.
  • Uber operates legally in Panama and picks up from designated areas at Tocumen Airport.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to Panama City

Depart from
Viru Viru International
Arrive to
Tocumen International
Average flights per week
259
Flight distance
Worth visiting
Panama Canal

Weekly direct flights

Discover the top airlines offering direct flights from Santa Cruz de la Sierra to Panama in the next month. You’ll find the number of daily direct flights per airline in the chart.

AirlineMon 02.02Tue 03.02Wed 04.02Thu 05.02Fri 06.02Sat 07.02Sun 08.02
Copa Airlines
---------------------
Weekly flights: 0 totalDaily flights: 0 averageMost flights: 0 flights
AirlineMon 09.02Tue 10.02Wed 11.02Thu 12.02Fri 13.02Sat 14.02Sun 15.02
Copa Airlines
2------------------
Weekly flights: 2 totalDaily flights: 0.29 averageMost flights: Monday 2 flights
AirlineMon 16.02Tue 17.02Wed 18.02Thu 19.02Fri 20.02Sat 21.02Sun 22.02
Copa Airlines
---------------------
Weekly flights: 0 totalDaily flights: 0 averageMost flights: 0 flights
AirlineMon 23.02Tue 24.02Wed 25.02Thu 26.02Fri 27.02Sat 28.02Sun 01.03
Copa Airlines
---------------------
Weekly flights: 0 totalDaily flights: 0 averageMost flights: 0 flights

Check-in for a flight from Santa Cruz de la Sierra to Panama

NameCarrier codeIATA CodePassport needed during booking
AviancaAVAAVNo
Boliviana de AviaciónBOVOBYes
Copa AirlinesCMPCMYes
LATAM AirlinesLANLAYes
Wingo airlinesRPBP5Yes

Online check-in is not available for these airlines.

Weather in Panama

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January28°C23°C
February29°C23°C
March29°C23°C
April30°C24°C
May29°C25°C
June29°C25°C
July29°C24°C
August28°C24°C
September28°C24°C
October28°C24°C
November27°C23°C
December28°C23°C
Hottest Month
30°C
April
Coldest month
23°C
January
Sunny days
161
days per year

14 day forecast

Saturday
7 Feb
87%
28°C22°C
14 Feb
31°C22°C
Sunday
8 Feb
82%
29°C23°C
15 Feb
71%
29°C22°C
Monday
9 Feb
88%
30°C22°C
16 Feb
83%
30°C22°C
Tuesday
10 Feb
89%
30°C23°C
17 Feb
85%
30°C24°C
Wednesday
11 Feb
84%
30°C23°C
18 Feb
88%
31°C23°C
Thursday
12 Feb
31°C22°C
19 Feb
86%
29°C23°C
Friday
13 Feb
31°C22°C
20 Feb
80%
28°C22°C
Book your trip to arrive at Tocumen International, Albrook Marcos A. Gelabert International, or Panamá Pacífico International Airport. The most popular airlines for this route are Avianca, Boliviana de Aviación, Copa Airlines, LATAM Airlines, and Wingo airlines. Santa Cruz de la Sierra and Panama have 259 direct flights per week.

Frequently asked questions

What are the most popular routes to and from Santa Cruz de la Sierra?
Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and London, Manchester, La Paz, Cochabamba, Sucre, Lima, São Paulo, Uyuni, Tarija, Miami, Madrid, Buenos Aires, Geneva, Philadelphia, Medellín, Washington, D.C., Montevideo, Salvador, Toronto, Cairo.
What are the most popular routes to and from Panama?
Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Medellín, London, Bogotá, Cartagena, San José, David, Chiriquí, Guatemala City, Cali, Miami, Cancún, Houston, New York, Boston, Mexico City, Los Angeles, Caracas, Lima, Vancouver, Barranquilla.
Which airports are there in Santa Cruz de la Sierra?
Santa Cruz de la Sierra is mainly served by Viru Viru International. But there are other airports nearby, including El Trompillo Airport.
What airports are near Panama?
The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.
Which airlines fly between Santa Cruz de la Sierra and Panama?
Currently, you can fly between Santa Cruz de la Sierra and Panama with Avianca, Boliviana de Aviación, Copa Airlines, LATAM Airlines, Wingo airlines.
When’s the best time to travel between Santa Cruz de la Sierra and Panama?
If you don’t have specific dates for your trip between Santa Cruz de la Sierra and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between Santa Cruz de la Sierra and Panama?
Traveling between Santa Cruz de la Sierra and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.
How many airports are there near Panama?
There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama.
What time do nonstop (direct) flights between Santa Cruz de la Sierra and Panama depart?
This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Santa Cruz de la Sierra, such as morning, afternoon, evening, or night, or select the exact hours for departure.
What time do nonstop (direct) flights between Santa Cruz de la Sierra and Panama arrive?
What time do flights between Santa Cruz de la Sierra and Panama depart?
What time do flights between Santa Cruz de la Sierra and Panama arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any origin and destination in the world by plane. Find the cheapest routes and best deals, as well as the best dates to travel.

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Flights from Santa Cruz de la Sierra

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The nearest countries with flights to Panama

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Other destination countries from Santa Cruz de la Sierra

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Airports near Santa Cruz de la Sierra

Airports near Panama

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