Cheap flights from Santander to Panama City from £536

Travelers frequently search for route combinations, such as Santander and Edinburgh, Birmingham, Barcelona, Bucharest, Madrid, Dubai, Lisbon, Prague, Tbilisi, Palma, Majorca, Vienna, Manila, Lagos, Santa Marta, Raleigh, Tirana, Dallas, Johannesburg, Bengaluru, Belgrade.

Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, Medellín, London, Bogotá, Cartagena, San José, David, Chiriquí, Guatemala City, Cali, Miami, Cancún, Houston, New York, Boston, Mexico City, Los Angeles, Caracas, Lima, Vancouver, Barranquilla.

The main airport in Santander is Santander. It is also served by Bilbao, Asturias, Santander, San Sebastián, Biarritz Pays Basque, Pamplona, Vitoria, Logroño–Agoncillo, Valladolid, León.

The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.

Currently, you can fly between Santander and Panama with Iberia Airlines, Avianca, Wingo airlines, Ryanair, Copa Airlines.

If you don’t have specific dates for your trip between Santander and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santander and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santander. The main one is Santander and other nearby airports include Bilbao, Asturias, Santander, San Sebastián, Biarritz Pays Basque, Pamplona, Vitoria, Logroño–Agoncillo, Valladolid, León

There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama.