St. Louis, MO to Guayaquil flights from £130

Flights starting at £130. Choose between Copa Airlines, Spirit Airlines, or American Airlines to find the best price.

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Travelers usually depart from St. Louis Lambert International, or St. Louis Union Station when they travel from St. Louis to Guayaquil. Book your trip to arrive at José Joaquín de Olmedo International, or Guayaquil Terminal Terrestre. The most popular airlines for this route are Copa Airlines, Spirit Airlines, American Airlines, Avianca, and Delta Air Lines. St. Louis and Guayaquil have 320 direct flights per week.

Check-in for a flight from St. Louis to Guayaquil

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
Copa AirlinesCMPCMYes0
0
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight
American AirlinesAALAAYesNo
AviancaAVAAVYesNo
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight

Ecuador COVID-19 travel restrictions

Your trip summary

Most travelers from St Louis, STL can enter Ecuador, but there are restrictions.

Departure

Visa requirements
  • No visa required
Forms and documents
  • Mandatory proof of vaccination for Ecuador
  • Mandatory proof of vaccination for the Galapagos Islands
  • Mandatory health declaration form
  • Mandatory traffic control card for the Galapagos Islands
Additional information
  • Masks are recommended in public

Return

Travel restrictions
  • Travel is allowed with restrictions for vaccinated travelers
  • No proof of negative pre-departure COVID-19 test results or recovery certificate
  • No quarantine required for vaccinated travelers
Visa requirements
  • No visa required
Forms and documents
  • Mandatory proof of vaccination for the United States
  • Mandatory travel attestation form

Information is provided as guidance only and accurate at the time of publishing. Always check government websites and airline materials before booking and traveling.

Learn more about COVID-19 restrictions in Ecuador in our dedicated Stories article.

Frequently asked questions

What are the most popular routes to and from St. Louis?
Travelers frequently search for route combinations, such as St. Louis and London, Manchester, Las Vegas, Dublin, San Jose, Orlando, Tampa, Washington, D.C., Glasgow, San Francisco, Houston, Minneapolis, Los Angeles, Detroit, Atlanta, Raleigh, Seattle, Edmonton, Vilnius, Adelaide.
What are the most popular routes to and from Guayaquil?
Travelers frequently search for route combinations, such as Guayaquil and London, Quito, Toronto, Montreal, Bogotá, Santiago de Chile, Manila, Vilnius, Cincinnati, São Paulo, Cali, Lima, Brisbane, Winnipeg, Hong Kong, Auckland, Singapore, Port of Spain, Fort Lauderdale, Calama.
What airports are near St. Louis?
The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Central Illinois Regional, MidAmerica St. Louis, Abraham Lincoln Capital, Williamson County Regional, Evansville Regional, Quincy Regional, Decatur, University of Illinois Willard.
What airports are near Guayaquil?
The main airport in Guayaquil is José Joaquín de Olmedo International. It is also served by José Joaquín de Olmedo International, Mariscal Lamar International, Eloy Alfaro International.
What buses and trains depart from St. Louis?
A number of bus and train companies depart from St. Louis, including Burlington Trailways, Greyhound, Amtrak train.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between St. Louis and Guayaquil?
Yes, it's possible to combine different modes of transport between St. Louis and Guayaquil thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between St. Louis and Guayaquil can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.
What is Virtual Interlining and how do I use it?
Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.
Which airlines fly between St. Louis and Guayaquil?
Currently, you can fly between St. Louis and Guayaquil with Copa Airlines, Spirit Airlines, American Airlines, Avianca, Delta Air Lines.
When's the best time to travel between St. Louis and Guayaquil?
If you don’t have specific dates for your trip between St. Louis and Guayaquil, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between St. Louis and Guayaquil?
How many airports are there near St. Louis?
How many airports are there near Guayaquil?
Is it possible to reach St. Louis by bus or train?
What time do nonstop (direct) flights between St. Louis and Guayaquil depart?
What time do nonstop (direct) flights between St. Louis and Guayaquil arrive?
What time do flights between St. Louis and Guayaquil depart?
What time do flights between St. Louis and Guayaquil arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

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