Cheap flights from Charleston to Santa Cruz de la Sierra from $325

Travelers frequently search for route combinations, such as Charleston and New York, Philadelphia, Tampa, Las Vegas, Orlando, Fort Myers, Los Angeles, San Juan, Denver, Cincinnati, Westchester County, New Orleans, San Diego, Fort Lauderdale, Phoenix, Boston, Pittsburgh, Dallas, Hartford, Detroit.

Travelers frequently search for route combinations, such as Santa Cruz de la Sierra and La Paz, Miami, Cochabamba, New York, Washington, D.C., Sucre, Los Angeles, Charlotte, Tarija, Uyuni, Santiago de Chile, Trinidad, Bogotá, Lima, Panama, Buenos Aires, Madrid, Rio de Janeiro, Guadalajara, Moline.

The main airport in Charleston is Charleston International. It is also served by Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Hilton Head, Florence Regional, Augusta Regional, Brunswick Golden Isles.

Currently, you can fly between Charleston and Santa Cruz de la Sierra with Spirit Airlines, Copa Airlines, Avianca, JetBlue Airways, LATAM Airlines.

If you don’t have specific dates for your trip between Charleston and Santa Cruz de la Sierra, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Charleston and Santa Cruz de la Sierra, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Charleston. The main one is Charleston International and other nearby airports include Charleston International, Myrtle Beach International, Savannah/Hilton Head International, Columbia Metropolitan, Hilton Head, Florence Regional, Augusta Regional, Brunswick Golden Isles

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Charleston, such as morning, afternoon, evening, or night, or select the exact hours for departure.

This depends on the airline’s flight schedule. You can easily select your preferred arrival time when you search on our website or mobile app. Choose the time of day you wish to arrive at Santa Cruz de la Sierra, such as morning, afternoon, evening, or night, or select the exact hours for arrival.