Cheap flights from San Luis Obispo to Santa Ana from $372

Travelers frequently search for route combinations, such as San Luis Obispo and Chicago, Seattle, Denver, Honolulu, Dubai, Indianapolis, Madrid, Palm Springs, San Antonio, Amsterdam, Redmond, Dallas, New York, Miami, Guadalajara, Cancún, Albuquerque, Nashville, Sacramento, San Salvador.

Travelers frequently search for route combinations, such as Santa Ana and Provo, San Francisco, Las Vegas, Seattle, Phoenix, Oakland, Vancouver, Denver, Eugene, Boise, New York, Idaho Falls, Medford, Des Moines, Dallas, Colorado Springs, Washington, D.C., Portland, London, New Orleans.

The main airport in San Luis Obispo is San Luis Obispo County Regional. It is also served by Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, San Luis Obispo County Regional, Santa Maria Public, Meadows Field.

The main airport in Santa Ana is John Wayne. It is also served by Tijuana International, San Diego International, John Wayne, Ontario International, Hollywood Burbank, Palm Springs International, Long Beach, Santa Barbara Municipal, McClellan–Palomar, Hawthorne Municipal.

Currently, you can fly between San Luis Obispo and Santa Ana with Alaska Airlines, United Airlines.

If you don’t have specific dates for your trip between San Luis Obispo and Santa Ana, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between San Luis Obispo and Santa Ana, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around San Luis Obispo. The main one is San Luis Obispo County Regional and other nearby airports include Fresno Yosemite International, Hollywood Burbank, Santa Barbara Municipal, Monterey Regional, San Luis Obispo County Regional, Santa Maria Public, Meadows Field

There are a number of airports in and around Santa Ana. The main one is John Wayne and other nearby airports include Tijuana International, San Diego International, John Wayne, Ontario International, Hollywood Burbank, Palm Springs International, Long Beach, Santa Barbara Municipal, McClellan–Palomar, Hawthorne Municipal.