Cheap flights from Santiago de los Caballeros to Panama City from $336

Travelers frequently search for route combinations, such as Santiago de los Caballeros and New York, San Juan, Atlanta, Fort Lauderdale, Orlando, Chicago, Washington, D.C., Tampa, Houston, Las Vegas, Miami, Cancún, Medellín, Lima, Mexico City, Berlin, Nassau, Seattle, Columbus, San José.

Travelers frequently search for route combinations, such as Panama and Houston, Miami, New York, Los Angeles, Boston, Detroit, Bocas Town, Bocas del Toro, Washington, D.C., Chicago, Denver, Atlanta, Las Vegas, Minneapolis, San Francisco, Medellín, Austin, Fort Lauderdale, Raleigh, Salt Lake City, Cincinnati.

The main airport in Santiago de los Caballeros is Cibao International. It is also served by Las Américas International, Cap-Haïtien International, Cibao International, Gregorio Luperón International, Samaná El Catey International, La Isabela International, La Romana International.

The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.

Currently, you can fly between Santiago de los Caballeros and Panama with JetBlue Airways, Copa Airlines, Spirit Airlines, Avianca, Wingo airlines.

If you don’t have specific dates for your trip between Santiago de los Caballeros and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santiago de los Caballeros and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santiago de los Caballeros. The main one is Cibao International and other nearby airports include Las Américas International, Cap-Haïtien International, Cibao International, Gregorio Luperón International, Samaná El Catey International, La Isabela International, La Romana International

There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama.