Cheap flights from Spokane to Knoxville from $256

Travelers frequently search for route combinations, such as Spokane and Las Vegas, Los Angeles, Phoenix, Guadalajara, Boston, Santa Ana, Medellín, Houston, Dar es Salaam, Kahului, Minneapolis, San Diego, Memphis, Bozeman, Chicago, Seattle, Cleveland, Detroit, Washington, D.C., Bishkek.

Travelers frequently search for route combinations, such as Knoxville and Orlando, Boston, Tampa, Fort Lauderdale, Las Vegas, San Francisco, Chicago, Austin, Phoenix, Guatemala City, Denver, New York, Los Angeles, Salt Lake City, St. Louis, Seattle, Richmond, London, Dallas, Kingston.

The main airport in Spokane is Spokane International. It is also served by Spokane International, Tri-Cities, Walla Walla Regional, Eastern Oregon Regional, Pangborn Memorial, Trail, Pullman–Moscow Regional, Lewiston–Nez Perce County, West Kootenay Regional.

The main airport in Knoxville is McGhee Tyson. It is also served by Nashville International, McGhee Tyson, Greenville–Spartanburg International, Asheville Regional, Chattanooga Metropolitan, Blue Grass, Tri-Cities Regional.

Currently, you can fly between Spokane and Knoxville with United Airlines, Alaska Airlines.

If you don’t have specific dates for your trip between Spokane and Knoxville, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Spokane and Knoxville, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Spokane. The main one is Spokane International and other nearby airports include Spokane International, Tri-Cities, Walla Walla Regional, Eastern Oregon Regional, Pangborn Memorial, Trail, Pullman–Moscow Regional, Lewiston–Nez Perce County, West Kootenay Regional

There are a number of airports in and around Knoxville. The main one is McGhee Tyson and other nearby airports include Nashville International, McGhee Tyson, Greenville–Spartanburg International, Asheville Regional, Chattanooga Metropolitan, Blue Grass, Tri-Cities Regional.