Cheap flights from Mexico City to Santiago de Chile from CA$343

Traveling between Mexico City and Santiago de Chile, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Mexico City. The main one is Mexico City International and other nearby airports include Mexico City International, Morelia International, Querétaro International, Puebla International, Toluca International

There are a number of airports in and around Santiago de Chile. The main one is Comodoro Arturo Merino Benítez International and other nearby airports include Comodoro Arturo Merino Benítez International.

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Mexico City, such as morning, afternoon, evening, or night, or select the exact hours for departure.

This depends on the airline’s flight schedule. You can easily select your preferred arrival time when you search on our website or mobile app. Choose the time of day you wish to arrive at Santiago de Chile, such as morning, afternoon, evening, or night, or select the exact hours for arrival.

This depends on the airline’s flight schedule. You can easily select your preferred departure time when you search on our website or mobile app. Choose the time of day you wish to depart from Mexico City, such as morning, afternoon, evening, or night, or select the exact hours for departure.

This depends on the airline’s flight schedule. You can easily select your preferred arrival time when you search on our website or mobile app. Choose the time of day you wish to arrive at Santiago de Chile, such as morning, afternoon, evening, or night, or select the exact hours for arrival.