Cheap flights from Des Moines to Panama City

Choose between Copa Airlines, American Airlines, or Delta Air Lines to find the best price

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Cheapest one-way trip

£167

Average round-trip

£235

Most popular airline

Copa Airlines

Travelers usually depart from Des Moines International, or Des Moines when they travel from Des Moines to Panama City. Book your trip to arrive at Tocumen International, or Albrook Marcos A. Gelabert International. The most popular airlines for this route are Copa Airlines, American Airlines, Delta Air Lines, United Airlines, and WN. Des Moines and Panama City have 283 direct flights per week.

Weekly flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Number of flights43544646-4747

Check-in for a flight from Des Moines to Panama City

NameCarrier codeIATA CodePassport needed during bookingAirport check-in closesOnline check-in available
Copa AirlinesCMPCMYesUnknownNo
American AirlinesAALAAYesUnknownNo
Delta Air LinesDALDLYesUnknownNo
United AirlinesUALUAYesUnknownNo
WNSWAWNNoUnknownNo

Frequently asked questions

What are the most popular routes to and from Des Moines?

Travelers frequently search for route combinations, such as Des Moines and São Paulo, Denver.

What are the most popular routes to and from Panama City?

Travelers frequently search for route combinations, such as Panama City and Bocas Town, Bocas del Toro, Lisbon, Rio de Janeiro, Changuinola, Bogotá, Curitiba, Santiago de Chile, Mexico City, San José, David, Chiriquí, São Paulo, Cuiabá, Navegantes, Cartagena, Quito, Guayaquil, Maceió, Fort Lauderdale, Belize City, New York.

What airports are near Des Moines?

The main airport in Des Moines is Des Moines International. It is also served by Eppley Airfield, Des Moines International, The Eastern Iowa, Southeast Iowa Regional, Waterloo Regional, Sioux Gateway, Kirksville Regional, Mason City Municipal, Fort Dodge Regional.

What airports are near Panama City?

The main airport in Panama City is Tocumen International. It is also served by Chitre Alonso Valderrama.

What buses and trains depart from Des Moines?

A number of bus and train companies depart from Des Moines, including Jefferson Lines.

Is it possible to combine flights, buses, and trains in one itinerary when traveling between Des Moines and Panama City?

What is Virtual Interlining and how do I use it?

Which airlines fly between Des Moines and Panama City?

When's the best time to travel between Des Moines and Panama City?

What flights operate between Des Moines and Panama City?

How many airports are there near Des Moines?

How many airports are there near Panama City?

Is it possible to reach Des Moines by bus or train?

What time do nonstop (direct) flights between Des Moines and Panama City depart?

What time do nonstop (direct) flights between Des Moines and Panama City arrive?

What time do flights between Des Moines and Panama City depart?

What time do flights between Des Moines and Panama City arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

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