Cheap flights from Knoxville to San Diego from £122

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1 stop
Fri, Nov 13
Knoxville TYSSan Diego SAN

£122
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1 stop
Thu, Nov 12
Knoxville TYSSan Diego SAN

£139
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1 stop
Sat, Nov 14
Knoxville TYSSan Diego SAN

£184
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1 stop
Tue, Nov 10
Knoxville TYSSan Diego SAN

£184
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1 stop
Sat, Nov 14 – Mon, Nov 16
Knoxville TYSSan Diego SAN

£315
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1 stop
Thu, Nov 12 – Sat, Nov 14
Knoxville TYSSan Diego SAN

£315
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How much do flights to San Diego cost?

Getting from San Diego airport to the city center

San Diego is served by San Diego International Airport (SAN), located just 5 km northwest of downtown San Diego. The airport offers convenient airport transfers to city center destinations via public transit, taxis, ride-hailing services, and rental cars. The MTS Bus Route 992 connects the airport to downtown and the Old Town Transit Center, where travelers can transfer to the San Diego Trolley. Journey times and costs vary depending on the mode of transport, time of day, and traffic conditions.

Notes:

  • Prices in USD; table created in 2025 and subject to change.
  • MTS Bus Route 992 operates between the airport and downtown via Old Town Transit Center.
  • Taxis and ride-hailing services pick up at designated areas outside each terminal.
  • Rental car facilities are located at the Rental Car Center, accessible via a free shuttle.
  • We recommend checking official transport websites for your travel planning.

Updated: December 2025

Key info about flying to San Diego

Depart from
McGhee Tyson
Arrive to
San Diego International
Average flights per week
178
Flight distance
Worth visiting
Griffith Observatory

Check-in for a flight from Knoxville to San Diego

NameCarrier codeIATA CodePassport needed during booking
-
Frontier AirlinesFFTF9No
WestJetWJAWSNo
JetBlue AirwaysJBUB6No
Alaska AirlinesASAASNo

Weather in San Diego

Average Weather

MonthAverage monthly max temperatureAverage monthly min temperature
January18°C10°C
February17°C10°C
March18°C11°C
April19°C12°C
May20°C14°C
June22°C16°C
July24°C18°C
August25°C19°C
September25°C19°C
October23°C16°C
November21°C13°C
December17°C11°C
Hottest Month
25°C
August
Coldest month
10°C
January
Sunny days
344
days per year

14 day forecast

Friday
30 Oct
59%
21°C19°C
6 Nov
22°C18°C
Saturday
31 Oct
72%
21°C18°C
7 Nov
24°C18°C
Sunday
1 Nov
80%
21°C17°C
8 Nov
26°C19°C
Monday
2 Nov
21°C17°C
9 Nov
26°C19°C
Tuesday
3 Nov
23°C17°C
10 Nov
26°C20°C
Wednesday
4 Nov
17%
22°C19°C
11 Nov
25°C20°C
Thursday
5 Nov
15%
21°C18°C
12 Nov
24°C20°C
Book your trip to arrive at San Diego International, or McClellan–Palomar. The most popular airlines for this route are Frontier Airlines, WestJet, JetBlue Airways, and Alaska Airlines. Knoxville and San Diego have 178 direct flights per week.

Frequently asked questions

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What are the most popular routes to and from San Diego?

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Which airlines fly between Knoxville and San Diego?

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What flights operate between Knoxville and San Diego?

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How many airports are there near San Diego?

What time do nonstop (direct) flights between Knoxville and San Diego depart?

What time do nonstop (direct) flights between Knoxville and San Diego arrive?

What time do flights between Knoxville and San Diego depart?

What time do flights between Knoxville and San Diego arrive?

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Flights from Knoxville

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