Orlando to St. Louis flights from £227

Flights starting at £227. Choose between American Airlines, Delta Air Lines, or Frontier Airlines to find the best price.

Why travel with Kiwi.com?
Best price

100+ million searches a day to find you the best available price.

Unique content

Explore unique options you won’t find anywhere else.

Travel hacks

Discover flight options and prices the airlines don’t want you to see.

Tips to know when travelling to St. Louis

Travelers usually depart from Orlando International, Orlando Sanford International, Orlando, FL Train Station, Winter Park, FL station, or Orlando when they travel from Orlando to St. Louis. Book your trip to arrive at St. Louis Lambert International, or St. Louis Union Station. The distance between Orlando and St. Louis is 1421 km. The most popular airlines for this route are American Airlines, Delta Air Lines, Frontier Airlines, Spirit Airlines, and United Airlines. Orlando and St. Louis have 202 direct flights per week.

Weekly direct flights

MondaysTuesdaysWednesdaysThursdaysFridaysSaturdaysSundays
Direct flights2222222
Fly direct with

Frontier Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Spirit Airlines on Mondays, Tuesdays, Wednesdays, Thursdays, Fridays, Saturdays, and Sundays.

Check-in for a flight from Orlando to St. Louis

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
American AirlinesAALAAYesNo
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight
Spirit AirlinesNKSNKNoOpens 24 days before flight
Closes 1 hours before flight
United AirlinesUALUAYesNo

St. Louis travel tips

1) Are you travelling with children? The City Museum in St. Louis awaits you

The City Museum is based on a 10-story building of the former International Shoe Factory. Artist Bob Cassilly bought the industrial premises. A few years later, he opened a museum here full of strange and useless things. Every meter of this unusual museum surprises its guests: you will see trains made of concrete mixers, a school bus in the air, and much more. Intricate passages, tunnels, labyrinths, and gyms in the aircraft fuselage will be interesting for active children. And, of course, everyone will be pleased with the circus performances and the Aquarium.

2) Get ready for high humidity in St. Louis

The air temperature in St. Louis is usually mild, but due to the Mississippi River, the humidity in the region is higher. This is especially acute in summer when the temperature reaches 30-35 degrees Celsius. Together with the high humidity, this makes long walks in St. Louis difficult.

3) Metro's light rail system in St. Louis consists of two lines

Metro's light rail system includes two lines (Red and Blue) that connect all the city’s main attractions. But neither line has stops in such famous districts as The Hill or Soulard. Both lines run from 4:15-4:30 to 01:00. A standard fare is $2.50 per adult.

United States COVID-19 travel restrictions

Kiwi.com

Latest COVID-19 restrictions

United States

Kiwi.com/COVID-19/United States
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Latest COVID-19 travel restrictions in United States – 06/2022
Your trip summary

Most travelers from Orlando, ORL with proof of full COVID-19 vaccination can enter St Louis, STL.

Departure

Travel restrictions
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Return

Travel restrictions
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required

  • No quarantine required

Information is provided as guidance only and accurate at the time of publishing. Always check government websites and airline materials before booking and traveling.

Learn more about COVID-19 restrictions in United States in our dedicated Stories article.

Frequently asked questions

How long does it take to travel from Orlando to St. Louis?
A one-way nonstop (direct) flight between Orlando and St. Louis takes around 2.5 hours.
What is the flight distance between Orlando and St. Louis?
The flight distance between Orlando and St. Louis is 1421 km.
What airlines offer nonstop (direct) flights between Orlando and St. Louis?
Several carriers operate flights between Orlando and St. Louis. Airlines offering nonstop (direct) flights include Frontier Airlines, Spirit Airlines.
What are the most popular routes to and from Orlando?
Travelers frequently search for route combinations, such as Orlando and London, Manchester, Buffalo, New York, San Juan, Dublin, Edmonton, Las Vegas, Calgary, Toronto, Chicago, Houston, Dallas, Washington, D.C., Edinburgh, Glasgow, New Orleans, Denver, Reykjavik, Atlanta.
What are the most popular routes to and from St. Louis?
Travelers frequently search for route combinations, such as St. Louis and London, Manchester, New York, Cebu, Atlanta, San Jose, Los Angeles, Edinburgh, Houston, San Francisco, Phoenix, Seattle, Portland, Denver, Dallas, Glasgow, Washington, D.C., Charlotte, Paris, Reykjavik.
Which airports are there in Orlando?
Orlando is mainly served by Orlando International. But there are other airports nearby, including Orlando Sanford International, Orlando Executive.
What airports are near Orlando?
The main airport in Orlando is Orlando International. It is also served by Tampa International, Jacksonville International, Southwest Florida International, St. Pete–Clearwater International, Sarasota–Bradenton International, Palm Beach International, Punta Gorda, Orlando Melbourne International, Daytona Beach International, Gainesville Regional.
What airports are near St. Louis?
The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Central Illinois Regional, Evansville Regional, MidAmerica St. Louis, Williamson County Regional, Quincy Regional, Abraham Lincoln Capital, Cape Girardeau Regional, Decatur.
What buses and trains depart from Orlando?
A number of bus and train companies depart from Orlando, including Jet Set Express, Greyhound, Amtrak train.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between Orlando and St. Louis?
What is Virtual Interlining and how do I use it?
Which airlines fly between Orlando and St. Louis?
When's the best time to travel between Orlando and St. Louis?
What flights operate between Orlando and St. Louis?
How many airports are there near Orlando?
How many airports are there near St. Louis?
Is it possible to reach Orlando by bus or train?
What time do nonstop (direct) flights between Orlando and St. Louis depart?
What time do nonstop (direct) flights between Orlando and St. Louis arrive?
What time do flights between Orlando and St. Louis depart?
What time do flights between Orlando and St. Louis arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

Explore alternative trips

Flights from Orlando

Flights to St. Louis

Popular routes

Find the best connection from Orlando to St. Louis

Search, compare, and book flights, trains, or buses to get there.

Search flights, trains & buses