Cheap flights from Santo Domingo to Tupelo from £254

Travelers frequently search for route combinations, such as Santo Domingo and London, Bogotá, Manchester, Medellín, Fort Lauderdale, Orlando, San Salvador, Mexico City, Atlanta, Cartagena, New York, San Juan, Philadelphia, Port-au-Prince, Miami, Los Angeles, Cancún, Madrid, Boston, Lower Prince's Quarter.

Travelers frequently search for route combinations, such as Tupelo and Philadelphia, New York, Charlotte, Phoenix, Nashville, Coxen Hole, Puerto Vallarta, Ciudad Juárez, San José, Malé, Las Vegas, Cartagena, Aruba, Boise, Malta, Providence, Pereira, Chișinău, Indianapolis, Little Rock.

Santo Domingo is mainly served by Las Américas International. But there are other airports nearby, including La Isabela International.

The main airport in Santo Domingo is Las Américas International. It is also served by Punta Cana International, Cibao International, Gregorio Luperón International, La Romana International, Samaná El Catey International.

The main airport in Tupelo is Tupelo Regional. It is also served by Memphis International, Birmingham-Shuttlesworth International, Huntsville International, Tupelo Regional, Jonesboro Municipal, Northwest Alabama Regional, McKellar–Sipes Regional, Meridian Regional, Golden Triangle Regional.

Currently, you can fly between Santo Domingo and Tupelo with Avianca, Spirit Airlines, VivaAerobus, Wingo airlines.

If you don’t have specific dates for your trip between Santo Domingo and Tupelo, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Santo Domingo and Tupelo, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Santo Domingo. The main one is Las Américas International and other nearby airports include Punta Cana International, Cibao International, Gregorio Luperón International, La Romana International, Samaná El Catey International