Cheap flights from Sioux Falls to Panama City from £171

Travelers frequently search for route combinations, such as Sioux Falls and Nashville, Davao, Orlando, Seattle, Burbank, Austin, Portland, Boston, San Francisco, Miami, Las Vegas, Vancouver, Honolulu, Zürich, Barcelona, Los Angeles, Greensboro, Fort Lauderdale, Denver, Budapest.

Travelers frequently search for route combinations, such as Panama and Bocas Town, Bocas del Toro, London, San José, Medellín, Cartagena, Bogotá, David, Chiriquí, Guatemala City, Cali, Houston, Lima, Los Angeles, Glasgow, Leeds, Birmingham, New York, Cancún, Miami, Mexico City, Barranquilla.

The main airport in Sioux Falls is Sioux Falls Regional. It is also served by Sioux Falls Regional, Watertown Regional, Sioux Gateway.

The main airport in Panama is Tocumen International. It is also served by Chitre Alonso Valderrama.

Currently, you can fly between Sioux Falls and Panama with Allegiant Air, Copa Airlines, Spirit Airlines, United Airlines, Avianca.

If you don’t have specific dates for your trip between Sioux Falls and Panama, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Sioux Falls and Panama, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Sioux Falls. The main one is Sioux Falls Regional and other nearby airports include Sioux Falls Regional, Watertown Regional, Sioux Gateway

There are a number of airports in and around Panama. The main one is Tocumen International and other nearby airports include Chitre Alonso Valderrama.