Cheap flights from Houston to Mayagüez from $188

Travelers frequently search for route combinations, such as Houston and Mexico City, Calgary, Guadalajara, New York, Los Angeles, Toronto, Chicago, Orlando, Las Vegas, Denver, Atlanta, Bogotá, Medellín, Vancouver, Miami, Tokyo, Dallas, Panama, Washington, D.C., Lima.

Travelers frequently search for route combinations, such as Mayagüez and San Juan, Orlando, Columbus, Key West, Denver, Boston, Cleveland, Seattle, Santo Domingo.

Houston is mainly served by George Bush Intercontinental. But there are other airports nearby, including William P. Hobby, Ellington, David Wayne Hooks Memorial Airport.

The main airport in Houston is George Bush Intercontinental. It is also served by Austin–Bergstrom International, Lake Charles Regional, Jack Brooks Regional, Easterwood, Victoria Regional.

The main airport in Mayagüez is Eugenio María de Hostos. It is also served by Luis Muñoz Marín International, Aguadilla Rafael Hernandez, Mercedita, Eugenio María de Hostos, Fernando Luis Ribas Dominicci.

Currently, you can fly between Houston and Mayagüez with Cape Air, Frontier Airlines, JetBlue Airways, Spirit Airlines, United Airlines.

If you don’t have specific dates for your trip between Houston and Mayagüez, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Houston and Mayagüez, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Houston. The main one is George Bush Intercontinental and other nearby airports include Austin–Bergstrom International, Lake Charles Regional, Jack Brooks Regional, Easterwood, Victoria Regional