Travelers usually depart from St. Louis Lambert International, or St. Louis Union Station when they travel from St. Louis to Santa Ana. Book your trip to arrive at John Wayne, or Santa Ana, CA Train Station. The most popular airlines for this route are WN, American Airlines, Frontier Airlines, United Airlines, and Delta Air Lines. St. Louis and Santa Ana have 173 direct flights per week.

Weekly flights

	Mondays	Tuesdays	Wednesdays	Thursdays	Fridays	Saturdays	Sundays
Number of flights	35	23	26	28	-	30	31

Check-in for a flight from St. Louis to Santa Ana

Name	Carrier code	IATA Code	Passport needed during booking	Airport check-in closes	Online check-in available
WN	SWA	WN	No	Unknown	No
American Airlines	AAL	AA	Yes	Unknown	No
Frontier Airlines	FFT	F9	No	Unknown	No
United Airlines	UAL	UA	Yes	Unknown	No
Delta Air Lines	DAL	DL	Yes	Unknown	No

Frequently asked questions

What are the most popular routes to and from St. Louis?

Travelers frequently search for route combinations, such as St. Louis and Orlando, Huntsville, Salvador, Curitiba, San Diego, San Jose.

What are the most popular routes to and from Santa Ana?

Travelers frequently search for route combinations, such as Santa Ana and Salt Lake City, Houston, São Paulo, Rio de Janeiro, Lisbon, Recife, Salvador, Fortaleza, Florianópolis, Foz do Iguaçu, Brasília, Belo Horizonte, João Pessoa, Paraíba, Porto Alegre, Porto, Goiânia, Maceió, Natal, Curitiba, Porto Seguro.

What airports are near St. Louis?

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Waynesville-St. Robert Regional, Abraham Lincoln Capital, Central Illinois Regional, Evansville Regional, MidAmerica St. Louis, Williamson County Regional, Quincy Regional, Columbia Regional.

What airports are near Santa Ana?

The main airport in Santa Ana is John Wayne. It is also served by San Diego International, Tijuana International, Ontario International, John Wayne, Hollywood Burbank, Palm Springs International, Long Beach, Santa Barbara Municipal, Imperial County, Meadows Field.

What buses and trains depart from St. Louis?

A number of bus and train companies depart from St. Louis, including Burlington Trailways, Amtrak train.

Is it possible to combine flights, buses, and trains in one itinerary when traveling between St. Louis and Santa Ana?

What is Virtual Interlining and how do I use it?

Which airlines fly between St. Louis and Santa Ana?

When's the best time to travel between St. Louis and Santa Ana?

What flights operate between St. Louis and Santa Ana?

How many airports are there near St. Louis?

How many airports are there near Santa Ana?

Is it possible to reach St. Louis by bus or train?

What time do nonstop (direct) flights between St. Louis and Santa Ana depart?

What time do nonstop (direct) flights between St. Louis and Santa Ana arrive?

What time do flights between St. Louis and Santa Ana depart?

What time do flights between St. Louis and Santa Ana arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

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