Cheap flights from Manchester to St. Louis from £424

Travelers frequently search for route combinations, such as Manchester and Jeddah, Barcelona, Istanbul, Tel Aviv, Düsseldorf, Amsterdam, Paris, Belfast, Islamabad, Lisbon, Madrid, Medina, Hamburg, Antalya, Copenhagen, Athens, Erbil, İzmir, Nice, Oslo.

Travelers frequently search for route combinations, such as St. Louis and London, Orlando, Las Vegas, Glasgow, Denver, New York, Los Angeles, Fort Lauderdale, San Diego, Calgary, Mexico City, Seattle, Cancún, Toronto, Charlotte, Washington, D.C., Minneapolis, Atlanta, Boston, Anchorage.

The main airport in Manchester is Manchester. It is also served by London Stansted, Luton, Manchester, Birmingham, Bristol, Newcastle, Liverpool John Lennon, Leeds Bradford, East Midlands, Isle of Man.

The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Evansville Regional, MidAmerica St. Louis, Central Illinois Regional, Abraham Lincoln Capital, Barkley Regional, Williamson County Regional, Quincy Regional, Waynesville-St. Robert Regional.

Currently, you can fly between Manchester and St. Louis with Ryanair, Frontier Airlines, Aer Lingus, WestJet, Air Transat.

If you don’t have specific dates for your trip between Manchester and St. Louis, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.

Traveling between Manchester and St. Louis, you can choose between direct (nonstop) flights or flights with one or more stops. You can select the number of stops on your journey, including an overnight stopover, and the duration of the stopover. What’s more, you can also select where you want to have your stopover. Want to say "Hi" to a friend in another city en route to your destination? Or fancy a quick round of shopping? Go Multi-City or Nomad and add places to your search that you wish to visit.

There are a number of airports in and around Manchester. The main one is Manchester and other nearby airports include London Stansted, Luton, Manchester, Birmingham, Bristol, Newcastle, Liverpool John Lennon, Leeds Bradford, East Midlands, Isle of Man

There are a number of airports in and around St. Louis. The main one is St. Louis Lambert International and other nearby airports include St. Louis Lambert International, General Wayne A. Downing Peoria International, Evansville Regional, MidAmerica St. Louis, Central Illinois Regional, Abraham Lincoln Capital, Barkley Regional, Williamson County Regional, Quincy Regional, Waynesville-St. Robert Regional.