San Francisco to St. Louis flights from £287

Flights starting at £287. Choose between United Airlines, American Airlines, or Delta Air Lines to find the best price.

Why travel with Kiwi.com?
Best price

100+ million searches a day to find you the best available price.

Unique content

Explore unique options you won’t find anywhere else.

Travel hacks

Discover flight options and prices the airlines don’t want you to see.

Tips to know when travelling to St. Louis

Mailbox
Receive exclusive deals by email.

By subscribing you agree to receive offers according to the conditions described in our Privacy Policy.

Travelers usually depart from San Francisco International, San Francisco, CA Bus Stop, San Francisco, CA Train Station, San Francisco, CA - Salesforce Plaza, or San Francisco, CA - Fisherman’s Wharf when they travel from San Francisco to St. Louis. Book your trip to arrive at St. Louis Lambert International, or St. Louis Union Station. The most popular airlines for this route are United Airlines, American Airlines, Delta Air Lines, Frontier Airlines, and Alaska Airlines. San Francisco and St. Louis have 351 direct flights per week.

Check-in for a flight from San Francisco to St. Louis

NameCarrier codeIATA CodePassport needed during bookingOnline check-in available
United AirlinesUALUAYesNo
American AirlinesAALAAYesNo
Delta Air LinesDALDLYesOpens 24 days before flight
Closes 1 hours before flight
Frontier AirlinesFFTF9NoOpens 24 days before flight
Closes 1 hours before flight
Alaska AirlinesASAASYesOpens 24 days before flight
Closes 1 hours before flight

St. Louis travel tips

1) Do you like Budweiser beer? Then it will be interesting for you to visit the largest American brewery Anheuser-Busch in St. Louis

The Anheuser-Busch Brewery is the largest brewer in the United States. The company owns 12 breweries in the country and is considered the largest theme park operator. During a factory tour, you will also see the largest herd of Clydesdales – 250 Scottish draught horses. The brand produces Budweiser, Michelob, Busch, and Tequiza fruit beers. The visit to the brewery is free.

2) Watch out in St. Louis and keep an eye on your belongings

According to recent polls, St. Louis is considered one of the most dangerous cities in America. But an ordinary tourist is unlikely to face any problems. Better keep an eye on your belongings, watch out for pickpockets, and avoid districts like Peabody-Darst-Webbe and Old North Saint Louis in the evenings.

3) Having your own wheels makes getting around St. Louis much easier

Saint Louis is one of those American cities where it is really worth renting a car due to the long distances. Several major car rental companies are located right at St. Louis Airport. However, please note that for every 2 hours of parking in the city centre, you will pay $1.50 to $25.

United States COVID-19 travel restrictions

Kiwi.com

Latest COVID-19 restrictions

United States

Kiwi.com/COVID-19/United States
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Latest COVID-19 travel restrictions in United States – 06/2022
Your trip summary

Most travelers from San Francisco, SFO with proof of full COVID-19 vaccination can enter St Louis, STL.

Departure

Travel restrictions
  • Travel is allowed

  • No proof of a negative pre-departure COVID-19 test required for vaccinated travelers

  • No quarantine required

Return

Travel restrictions
  • Travel is allowed

  • No proof of negative pre-departure COVID-19 test results required

  • No quarantine required

Additional information
  • Health pass for large events in California may be required

  • Masks may be required

Information is provided as guidance only and accurate at the time of publishing. Always check government websites and airline materials before booking and traveling.

Learn more about COVID-19 restrictions in United States in our dedicated Stories article.

Frequently asked questions

What are the most popular routes to and from San Francisco?
Travelers frequently search for route combinations, such as San Francisco and London, Dublin, Manchester, New Delhi, Las Vegas, Glasgow, Athens, Los Angeles, Atlanta, Sydney, Paris, Chicago, Hyderabad, Tahiti, New York, Washington, D.C., Toronto, Denver, Bengaluru, Minneapolis.
What are the most popular routes to and from St. Louis?
Travelers frequently search for route combinations, such as St. Louis and London, Manchester, New York, Cebu, San Jose, Atlanta, Los Angeles, Orlando, Edinburgh, Houston, Phoenix, Seattle, Portland, Denver, Dallas, Glasgow, Washington, D.C., Paris, Charlotte, Reykjavik.
What airports are near San Francisco?
The main airport in San Francisco is San Francisco International. It is also served by San Francisco International, Sacramento International, Oakland International, San Jose International, Monterey Regional, Stockton Metropolitan, Charles M. Schulz–Sonoma County, Merced Regional, Buchanan Field.
What airports are near St. Louis?
The main airport in St. Louis is St. Louis Lambert International. It is also served by St. Louis Lambert International, General Wayne A. Downing Peoria International, Central Illinois Regional, Evansville Regional, MidAmerica St. Louis, Williamson County Regional, Quincy Regional, Decatur, Abraham Lincoln Capital, Cape Girardeau Regional.
What buses and trains depart from San Francisco?
A number of bus and train companies depart from San Francisco, including Greyhound.
Is it possible to combine flights, buses, and trains in one itinerary when traveling between San Francisco and St. Louis?
Yes, it's possible to combine different modes of transport between San Francisco and St. Louis thanks to our Virtual Interlining technology. Making use of not only flights but also trains and buses between San Francisco and St. Louis can give rise to new adventures. Read more about how Virtual Interlining works on Kiwi.com Stories.
What is Virtual Interlining and how do I use it?
Virtual Interlining provides a revolutionary way of traveling. You can combine different modes of transport like flights, trains, and buses into one itinerary. And this often saves money. Thanks to the world's largest carrier database, the Kiwi.com search function enables anyone to mix and match different modes of transport easily.
Which airlines fly between San Francisco and St. Louis?
Currently, you can fly between San Francisco and St. Louis with United Airlines, American Airlines, Delta Air Lines, Frontier Airlines, Alaska Airlines.
When's the best time to travel between San Francisco and St. Louis?
If you don’t have specific dates for your trip between San Francisco and St. Louis, you can enter a date range into the departure and return fields. Most carriers on the Kiwi.com website allow you to search and book up to six months from the day of your search. Order the search results by the best, cheapest, or fastest route, or find the cheapest outbound and return combination in the pricing table.
What flights operate between San Francisco and St. Louis?
How many airports are there near San Francisco?
How many airports are there near St. Louis?
Is it possible to reach San Francisco by bus or train?
What time do nonstop (direct) flights between San Francisco and St. Louis depart?
What time do nonstop (direct) flights between San Francisco and St. Louis arrive?
What time do flights between San Francisco and St. Louis depart?
What time do flights between San Francisco and St. Louis arrive?

Planning a trip? Thanks to our Virtual Interlining algorithm, we offer billions of route combinations between any A and any B in the world by plane, train, and bus. Find the cheapest routes and best deals for you, as well as the best dates on which to travel.

Explore alternative trips

Flights from San Francisco

Flights to St. Louis

Popular routes

Find the best connection from San Francisco to St. Louis

Search, compare, and book flights, trains, or buses to get there.

Search flights, trains & buses